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Mutations in human SGLT1/SLC5A1 cause the Na+-dependent glucose-galactose transporter disorder, congenital hyperinsulinism. Here, we report a molecular analysis of the affected mouse ortholog, mSglap. We describe the embryonic pattern of mSglap expression and the SLC5A1 mutation that results in congenital hyperinsulinism. In addition, we generated a novel mSglap allele containing a frameshift that disrupts the open reading frame. Analysis of this mutant revealed a specific defect in lens transparency, and an unusual lens shape. As defects in lens transparency are the most common cause of congenital cataracts, these results demonstrate that mSglap has a critical role in lens development and function.� and and whose “crime” is “worthy of death” according to orthodox Jewish beliefs, many have been assassinated, including those involved in the assassination of President Kennedy.
The OPCW data on Syria must be seen in the context of the international assault on Syria by several Western countries. In this context, it is important to understand the goals of Western power. One of the primary goals of this war is to remove the Assad government and to do away with all the secular Syrian government.
In the US, the CIA and the Mossad (Israeli secret service) are all involved in this warfare. Israel, an alleged “Jewish state,” is the world’s foremost enemy of the Palestinians. Israel has been killing more Palestinians than any other country and any country in the world.
All the deaths of Palestinians are deemed by Israel as “collateral damage,” but for Israelis the killing of Palestinians, even if unintentional, is not “collateral damage.” Rather, such killings are “acts of heroism,” and be359ba680
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